Dados do Trabalho

Título

Serial evaluation of the SOFA score to predict outcome in COVID-19 patients

Objetivo

To evaluate trends in organ dysfunction in patients with COVID-19 by using
the Sequential Assessment of Organ Dysfunction (SOFA) scores and compare their
results to those of an heterogenous population of criticality ill patients.

Métodos

Observational, single-center cohort study. A total of 1213 adult patients admitted to the
ICU with severe or critical forms of COVID-19 and measures of SOFA scores available
at least on the first and second days after ICU admission were included. Clinical and
laboratory data and outcomes were collected from electronic medical records. The
heterogenous population of criticality Ill patients reported in the original study was
used for comparisons.

Resultados

Median age was 55 [42-67] year, SAPS 3 53 [45-67],
66% was on mechanical ventilation and 60% needed vasopressor support. The initial,
highest, and mean SOFA scores correlated well with hospital mortality. Initial SOFA
scores higher than 7 were associated with hospital mortality rates higher than 60%. If
higher than 11, mortality surpassed 80%. Mortality was 80% in patients with more than
8 of SOFA score on admission with no change or worsening valise, but decreased to
20% if SOFA score was higher than 8 but decreased within 48 h after admission.

Conclusão

Sequential assessment of organ dysfunction during the first few days of
ICU admission is a good indicator of prognosis in patients with COVID-19. These results
are similar to those reported originally in an heterogenous population of critically ill
patients.