Dados do Trabalho

Título

Epidemiological profiling of Septic patients admitted to the ICU: a multicentric study.

Objetivo

To describe the clinical-epidemiological profile of septic patients, without shock, admitted to an Intensive Care Unit (ICU) in two tertiary hospitals.

Métodos

Multicentric cross-sectional study conducted in two hospitals – one in Brazil and the other in Italy – that included adult patients admitted to the ICU. Variables age, sex, site of infection, ICU and hospital length-of-stay and SAPS 3 score were collected. All patients were followed until hospital discharge or death. We also collected variables regarding ICU readmission, patient evolution to shock, need for mechanical ventilation and renal substitutive therapy. Statistical analysis of the collected data was carried out using descriptive statistics with categorical variables being reported as counts and percentages, and continuous variables as means with standard deviations or medians with interquartile ranges.

Resultados

We included 102 patients. The median age was 75.0 (62.0–84.0) years, with a predominance of males (n=56; 55%). The mean SAPS 3 score was 55.5.0±14.45. The main site of infection was pulmonary (n=40; 40%), followed by abdominal (n=28; 27.4%) and urinary (n=18; 17.6%). The median length of stay in the ICU and hospital was 7.5 (3.6–10.85) days and 19 (9.62–44.22) days, respectively. During hospital stay 23.5% of patients were readmitted to the ICU, 70% needed vasopressor, 51% mechanical ventilation and 24.5% renal substitutive therapy; 48% of patients died.

Conclusão

Sepsis remains a serious condition and an adequate profiling of ICU-admitted patients may aid Intensivists in optimizing better resource allocation and improving outcomes.