Dados do Trabalho


Título

SAPS 3 as a mortality predictor for Septic patients without Shock in Brazil and Italy: is it a got surrogate for outcomes?

Objetivo

To compare SAPS 3 score mortality prediction to real data in septic patients admitted to Intensive Care Units.

Métodos

Multicentric cohort conducted in two hospitals, one in Italy and the other in Brazil, which followed patients until hospital discharge or death. We collected data on age, reason for Intensive Care Unit (ICU) admission, length of hospital and ICU stay and variables needed to calculate SAPS 3 score. We recorded patient outcomes and compared real with predicted mortality. Statistical analysis of the collected data was carried out using descriptive statistics with categorical variables being reported as counts and percentages, and continuous variables as means with standard deviations or medians with interquartile ranges.

Resultados

We included 102 patients. The median age was 75.0(62.0–84.0) years, the main reason for ICU admission was acute respiratory failure (35;34%). The median length of stay in the ICU and hospital was 7.5(3.6–10.85) days and 19 (9.62–44.22) days, respectively. Mean SAPS 3 score was 55.5.0±14.45 and the predicted score mortality was 25.7%. Our cohort real absolute mortality was 49%.

Conclusão

SAPS 3 absolute mortality prediction underestimated our cohort actual mortality. This may have happened due to a higher median age and number of comorbidities in admitted patients, together with local disparities in hospital settings between Brazil and Italy. The findings of this study do not support SAPS 3 as a good surrogate for mortality prediction in our sample and this speaks in favor to a already underway score recalibration.

Área

Sepse e infecção

Autores

Viviane Solano Lutif, Beatriz Amorim Beltrão, Denise Battaglini, Greta Zunino, Juliana Saboia de Senna, Marcio Manozzo Boniatti, Diego Bastos Porto